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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCFC1 All Species: 13.33
Human Site: Y174 Identified Species: 26.67
UniProt: P51610 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51610 NP_005325.2 2035 208732 Y174 P R Y L N D L Y I L E L R P G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088011 1702 173511
Dog Lupus familis XP_867443 2039 208943 Y174 P R Y L N D L Y I L E L R P G
Cat Felis silvestris
Mouse Mus musculus Q61191 2045 210519 Y174 P R Y L N D L Y I L E L R P G
Rat Rattus norvegicus Q5RKG2 723 79130
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509058 2033 207643 G161 S K L V I Y G G M S G C R L G
Chicken Gallus gallus XP_001234928 787 86020
Frog Xenopus laevis NP_001087989 2101 219049 Y172 P R Y L N D L Y I L E L R A G
Zebra Danio Brachydanio rerio Q7ZUV7 1173 122182
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4C8 1500 160166
Honey Bee Apis mellifera XP_624189 1550 166762
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791039 1216 126587
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 82.3 93.8 N.A. 93.7 24.2 N.A. 82.4 26.3 68.8 20.4 N.A. 33 34.2 N.A. 37
Protein Similarity: 100 N.A. 82.5 95 N.A. 95.5 30 N.A. 86 32.2 76.6 33.1 N.A. 47.5 50.2 N.A. 46.5
P-Site Identity: 100 N.A. 0 100 N.A. 100 0 N.A. 13.3 0 93.3 0 N.A. 0 0 N.A. 0
P-Site Similarity: 100 N.A. 0 100 N.A. 100 0 N.A. 33.3 0 93.3 0 N.A. 0 0 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 34 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 9 0 0 9 0 0 0 42 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 34 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 34 0 0 34 0 0 34 0 34 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 34 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 34 0 0 0 0 0 0 0 0 0 0 42 0 0 % R
% Ser: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 34 0 0 9 0 34 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _